Chika Lab.
Department of Environmental Health, Faculty of Pharmaceutical Sciences
TOHO University
2009年
2
Suppression of fibroblast growth factor-2 expression: Possible mechanism underlying methylmercury-induced inhibiton of the repair of wounded monolayers of cultured human brain microvascular endothelial cells
Hirooka T., Fujiwara, Y., Inoue S., Shinkai Y., Yamamoto C., Satoh, M., Yasutake, A., Eto, K., and Kaji, T.
The Journal of Toxicological Sciences, 34, 433-439, 2009
1
Homocysteine inhibits proteoglycan synthesis in cultured bovine aortic smooth muscle cells
Fujiwara, Y., Mikami, C., Nagai, M., Yamamoto, C., Hirooka, T., Satoh, M. and Kaji, T.
Journal of Health Science, 54, 56-65, 2009
2008年
4
Adiponectin as an inducer of decorin synthesis in cultured vascular smooth muscle cells
Yamamoto, C., Urano, A., Fujiwara, Y., and Kaji, T.
Life Sciences, 83, 447-452, 2008
3
Arsenite but not arsenate Inhibits general proteoglycan synthesis in cultured arterial smooth muscle cells
Fujiwara, Y., Yamamoto, C., Hirooka, T., Terada, N., Satoh, M., and Kaji, T.
Journal of Health Science, 33, 487-492, 2008
2
Biological activities of exogenous polysaccharides via controlling endogenous proteoglycan metabolism in vascular endothelial cells
Sato, T., Yamamoto, C., Fujiwara, Y., and Kaji, T.
Yakugaku Zasshi, 128, 717-723, 2008
1
Proteoglycan as a key molecule in atherosclerosis progression: characteristics of the structure and regulation of the synthesis
Urano, A., Yamamoto, C., Fujiwara, Y., and Kaji, T.
Yakugaku Zasshi, 128, 365-375, 2008
2007年
1
Methylmercury retards the repair of wounded monolayer of human brain microvascular endothelial cells by inhibiting their proliferation without nonspecific cell damage
Hirooka, T., Fujiwara, Y., Yamamoto, C., Yasutake, A., and Kaji, T.
Journal of Health Science, 53, 450-456, 2007
2006年
3
The vascular endothelial growth factor VEGF165 induces perlecan synthesis via VEGF receptor-2 in cultured human brain microvascular endothelial cells
Kaji, T., Yamamoto, C., Oh-i, M., Fujiwara, Y., Yamazaki, Y., Morita, T., Plaas, A.H., and Wight, T.N.
Biochimica et Biophysica Acta, 1760, 1465-1474, 2006
2
Colominic acid inhibits the proliferation of cultured bovine aortic endothelial cells and injures their monolayers: cell density-dependent effects prevented by sulfation
Yamamoto, C., Morita, Y., Yamaguchi, S., Hayashi, T., and Kaji, T.
Life Sciences, 78, 844-850, 2006
1
The biological effects of depolymerized sodium spirulan and sulfated colominic acid on vascular cells are beneficial in preventing atherosclerosis
Yamamoto, C., Fujiwara, Y., and Kaji, T.
Journal of Health Science, 52, 205-210, 2006
2005年
5
Proteoglycans predominantly synthesized by human brain microvascular endothelial cells in culture are perlecan and biglycan
Yamamoto, C., Deng, X., Fujiwara, Y., and Kaji, T.
Journal of Health Science, 51, 576-583, 2005
4
Inhibition of cultured bovine aortic smooth muscle cell proliferation by colominic acid
Yamamoto, C., Yamaguchi, S., Hayashi, T., and Kaji, T.
Biological and Pharmaceutical Bulletin, 28, 994-997, 2005
3
Induction of synthesis of a large heparan sulfate proteoglycan, perlecan, by thrombin in cultured human coronary smooth muscle cells
Yamamoto, C., Wakata, T., Fujiwara, Y., and Kaji, T.
Biochimica et Biophysica Acta, 1722, 92-102, 2005
2
Selective promotion of plasminogen activator inhibitor-1 secretion by activation of proteinase-activated receptor-1 in cultured human brain microvascular pericytes: comparison with endothelial cells
Yamamoto, C., Sugato, M., Fujiwara, Y. and Kaji, T.
Biological and Pharmaceutical Bulletin, 28, 208-211, 2005
1
Proteoglycans released from cultured bovine aortic endothelial cell layers by sodium spirulan are both perlecan and biglycan
Yamamoto, C., Shimada, S., Fujiwara, Y., Lee, J.B., Hayashi, T., and Kaji, T.
Biological and Pharmaceutical Bulletin, 28, 32-36, 2005
2004年
3
Characterization of chondroitin/dermatan sulfate proteoglycans synthesized by bovine retinal pericytes in culture
Kaji, T., Sakurai, S., Yamamoto, C., Fujiwara, Y., Yamagishi, S., Yamamoto, H., Kinsella, M.J., and Wight, T.N.
Biological and Pharmaceutical Bulletin, 27, 1763-1768, 2004
2
Differential regulation of biglycan and decorin synthesis by connective tissue growth factor in cultured vascular endothelial cells
Kaji, T., Yamamoto, C., Oh-i, M., Nishida, T., and Takigawa, M.
Biochemical and Biophysical Research Communications, 322, 22-28, 2004
1
Sodium spirulan as a potent inhibitor of arterial smooth muscle cell proliferation in vitro
Kaji, T., Okabe, M., Shimada, S., Yamamoto, C., Fujiwara, Y., Lee, J.B., and Hayashi, T.
Life Sciences., 79, 2431-2439, 2004
2003年
3
Analysis of chondroitin/dermatan sulfate microstructure in cultured vascular smooth muscle cells after exposure to lead and cadmium
Fujiwara, Y., Yamamoto, C., Kaji, T. and Plass, A.H.
Journal of Health Science, 49, 534-540, 2003
2
Differential effects of sodium spirulan on the secretion of fibrinolytic proteins from vascular endothelial cells: enhancement of plasminogen activator activity
Yamamoto, C., Nakamura, A., Shimada, S., Kaji, T., Lee, J.B. and Hayashi, T.
Journal of Health Science, 49, 405-409, 2003
1
Vascular smooth muscle cells in culture express tumor necrosis factor-α that suppresses collagen synthesis depending on cell density
Kaji, T., Hiraga, S., Yamamoto, C., Fujiwara, Y., Ueda, Y, Zisaki, F., Iwata, K., Katsuda, S., and Nakanishi, I.
Journal of Health Science, 49, 115-122, 2003
2002年
6
Effects of tumor necrosis factor-α on the synthesis of DNA, the secretion of matrix metalloproteinases/tissue inhibitors of metalloproteinases, and the activity of invasive migration in cultured vascular smooth muscle cells
Kaji, T., Hiraga, S., Yamamoto, C., Fujiwara, Y., Ueda, Y., Zisaki, F, Iwata, K., Okada, Y., and Katsuda, S
Journal of Health Science, 48, 354-358, 2002
5
Inhibition of the association of proteoglycans with cultured vascular endothelial cell layers by calcium and sodium spirulan
Kaji, T., Shimada, S., Yamamoto, C., Fujiwara, Y., Lee, J.B., and Hayashi, T.
Journal of Health Science, 48, 250-255, 2002
4
Induction of plasminogen activator inhibitor type 1 synthesis by cadmium in human vascular endothelial cells in culture
Yamamoto, C., and Kaji, T.
Journal of Health Science, 48, 55-61, 2002
3
Inhibition of cultured bovine aortic endothelial cell proliferation by sodium spirulan, a novel sulfated polysaccharide isolated from Spirulina platensis
Kaji, T., Fujiwara, Y., Hamada, C., Yamamoto, C., Shimada, S., Lee, J.B., and Hayashi, T.
Planta Medica, 68, 505-509, 2002
2
Repair of wounded monolayers of cultured bovine aortic endothelial cells is inhibited by calcium spirulan, a novel sulfated polysaccharide isolated from Spirulina platensis
Kaji, T., Fujiwara, Y., Inomata, Y., Hamada, C., Yamamoto, C., Shimada, S., Lee J.B., and Hayashi, T.
Life Sciences, 70, 1841-1848, 2002
1
Differential effects of cadmium on proteoglycan synthesis of arterial smooth muscle cells: increase in small dermatan sulfate proteoglycans, biglycan and decorin, in the extracellular matrix at low cell density
Fujiwara, Y., Tsumura, N., Yamamoto, C., and Kaji, T.
Toxicology, 170, 89-101, 2002
2001年
1
Mechanical strain induces specific changes in the synthesis and organization of proteoglycans by vascular smooth muscle cells
Lee, R.T., Yamamoto, C., Feng, Y., Potter-Perigo, S., Briggs, W.H., Landschulz, K.T., Turi, T.G., Thompson, J.F., Libby, P., and Wight, T.N.
The Journal of Biological Chemistry, 276, 13847-13851, 2001
2000年
3
Selective increase in decorin core mRNA level in cultured vascular smooth muscle cells after exposure to advanced glycation endproducts
Kaji, T., Miyajima, S., Yamamoto, C., Fujiwara, Y., Sakurai, S., Yamagishi, S., Sueishi, K., and Yamamoto, H.
Journal of Health Science, 46, 223-227, 2000
2
Proteoglycans synthesized by cultured bovine aortic smooth muscle cells after exposure to lead: lead selectively inhibits the synthesis of versican, a large chondroitin sulfate proteoglycan
Fujiwara, Y., Yamamoto, C., and Kaji, T.
Toxicologhy, 154, 9-19, 2000
1
Cell density-dependent regulation of proteoglycan synthesis by transforming growth factor-β1 in cultured bovine aortic endothelial cells
Kaji, T., Yamada, A., Miyajima, S., Yamamoto, C., Fujiwara, Y., Wight, T.N., and Kinsella, M.G.
The Journal of Biological Chemistry, 275, 1463-1470, 2000